Sunday, August 09, 2009

Deer And Sassafras In Their Diet. Is the Plant Smarter Than We Think.

 Who eats sassafras, what parts, and what does the sassafras do in return.
Does enhanced toxicity result in labs using the same test plants over and over?


Anthropo-plantism

Here, look at deer and rodents who eat part of the sassafras (for some leaves are toxic, for others, roots are toxic, for others bark is toxic, etc.  What does the plant do to defend itself against being totally consumed. This research suggests that some plants become more toxic to the eater, the more it is eaten.

Apply that to the lab setting. Suppose somebody brought in a sassafras shrub, to use as food to test for tumors. Same shrub, over and over, strip off parts to feed to the poor critters in the cages.  What does the sassafras do to protect itself? Become even more toxic?  And what does that do to the lab results.  More tumors than would ordinarily occur.  Question Asked But Un-Answered. Yet.  Also note in the New York Times, Tuesday October 27, 2009, at D2, article by Nicholas Wade"
"Mice are very prone to cancer; in some strains, 90 percent of them die of tumors.  People have stronger defenses against cancer, as is necessary for a long-lived animal; the disease accounts for 23 percent of human mortality.  But the mole rat has taken its anticancer defenses even further: it seems not to get the disease at all."
What if they were fed sassafras? The mole rats seem to have a double immune system, says the article.  We should study that, instead of why the lab test mice get the tumors so fast.


I. DEER
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A.  What do deer eat, and why do they eat what they do. 

Deer do eat sassafras. If safrole in sassafras is so toxic to mammals, why don't deer get sick.

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Herbivores. Deer are classified as Cervidae, which means that they eat vegetation, and, incidentally, also shed their antlers each year. As herbivores, they have "compound stomachs" - see://www.oswego.edu/wscp/DEER.htm/- as do moose, and elk.

The compound stomachs enable the deer to eat woody things - like sassafras in the winter, spring, summer (not fall, when they have to fatten up), for those who do eat it -  that other creatures would find indigestible. See http://www.agfc.com/pdfs/free/whatdeereat_bro.pdf/. The stomachs have great scrabble names: learn them. "rumen, reticulum, omasum and abomasum." See ://www.oswego.edu/wscp/DEER.htm/

The rumen breaks down the browse first. The microflora there start a fermentation process. So, its food cannot exude something that will inhibit the fermentation - act like an antibacterial agent. Is that an issue with some woody things? Yes. Woody things or needles from some evergreens have high essential oil content, and essential oils are difficult to digest (Douglas fir, Juniper). So, deer don't pig out on those, but eat lots of things lightly, when they can.
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Moose Crossing, Quebec

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B.  Their stomachs can break the plant components down.  

 The chemical "building blocks" of the browse:  These also are important to the diet. More names here: lignin and cellulose (both hard to digest), hemicellulose, carbohydrates and proteins (easier). Some of those are unfamiliar, but too much of the lignin in the diet, for example, can cause weight loss and death. Some tolerated well, lots not.

So, an animal's diet also reflects what it is able to digest. Go far afield from that, and the animal is in trouble.  Nature doesn't need labs to tell us what to eat, necessarily. Would we not limit ourselves to so much root beer a day?

C.  They limit what they eat perhaps because of an anti-herbivore defense:

Some plants develop toxins, so that the preferred foods are not necessarily the most nutritious, but the least toxic. Here is the process:  http://www.tulane.edu/~ldyer/classes/406/koricheva.pdf/  See also ://www.oswego.edu/wscp/DEER.htm/ again,   Good site.  Browsing itself can cause the regrowth to be more toxic than the first growth. Deer like tips best. Browsing nips growth in the bud, literally, so helps keep the food supply coming - it the tree gets too high (over 10 feet, say) then the deer can't reach it.

Deer are not just "browsing herbivores", however; they also eat corn and soybeans and acorns and crabapples and other "grazer-browser" foods. They like variety. See ://www.fs.fed.us/database/feis/plants/tree/sasalb/all.html/.  Animal wisdom.

Deer are like us. Look at the categories of foods they eat. There is a chart at the DEER site showing what they eat as to the following:

Food Categories

1. Preferred (roast chicken)
2. Staple (potatoes)
3. Emergency (tofu)
4. Stuffing (no, not Doritos. This category is what you stuff with when you are starving, so, say gruel and more gruel, like Oliver )
5. Pastime (peanut butter)

So:  Deer do eat sassafras. 

White-tailed New York State deer (as opposed to other areas, or the mule deer variety) prefer mountain sassafras. Massachusetts white-tails will eat it but do not prefer it. You can tell whether a deer ate a twig and not a rabbit, because the deer's stubby end will be left raggy, and the rabbit's stubby end will be clean-cut. See ://www.oswego.edu/wscp/DEER.htm

Does mere indigestibility explain why they do not eat more, or is it a search for balance in the enzymes, or is there a natural toxicity as well. Something can be indigestible without being poisonous or toxic.

See your living room in a new way. Plants do supposedly develop defenses against
  • those who clip or threaten it, see ://ming.tv/flemming2.php/__show_article/_a000010-001034.htm/ ; 
  • or eat it, see Madagascar and its plants' anachronistic tactics against birds, that continue even though the birds are extinct, at ://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2275176/. 
  • threats to come, by means of plant gossip (isn't this fun?), see ://www.sciencenetlinks.com/sci_update.php?DocID=168/ - passing on early warnings so the fellows downwind can rev up the chemical defenses for the future disaster
  •   or at least reaction to "pain" - urban legend? A little too much anthropoplantism? See ://www.abovetopsecret.com/forum//thread318914/pg1.
You have to love it. Why be a "professional" when you could be a plantsperson.

But none who eat sassafras overdo it on their own, even when starving. It is not a "stuffer" browse.

Even in good times, some animals eat some parts of the sassafras - this one is a leaf guy, that one a twig guy, the other one a root kind of guy, some others, but nobody pigs out. For animals, none seem to eat sassafras so much as to be important. See ://www.fs.fed.us/database/feis/plants/tree/sasalb/all.html/ Animal wisdom.

So:  The Safrole Connection.  We are branching out to deer, because safrole oil overdosed in rats brought on tumors, we are told. http://www.heart-disease-bypass-surgery.com/data/articles/104.htm/. Do animals just monitor their own intake of diet matter? Why can't we as well?

We wouldn't overdo root beer. Perhaps that is because it does develop a toxicity if it is overdone? Or the animal itself, like us, prefers variety and would never eat nothing but.

Why don't they eat more?  It is all around.

Is the deer diet a self-imposed limit because the plant itself has put up more defenses than we realize.  Some plants defend against being eaten by becoming more toxic under siege.

We did find that the deer eat evergreens - rhododendron, kinds of needley things.  And this idea came up. Scientists know that some plants that are being eaten up, like the needley things in winter when the deer are going at them, will increase in toxicity.  The stuff that is not good for the deer gets stronger when the plant is being repeatedly nibbled. They tested by also doing snipping on their own - the woodsmen.  Then testing the result.  Sure enough.  The toxicity increased - a kind of defense against being eaten to death.

See ://www.oswego.edu/wscp/DEER.htm/:

Heavy continuous browsing on plant twigs can retard vegetative growth or even kill the plants.  Browsing may also cause subsequent re-growth to contain higher levels of toxic compounds.

Sassafras has another attraction for deer over rodents. The teeth of deer do not keep growing, as do rodent teeth, requiring constant gnawing.  No wonder deer are less "fended off" than rodents, if that is so.  Deer can eat the softer plants without dental problems. See  ://www.americazoo.com/goto/index/mammals/rodentia.htm/ Note the comments on the love-hate relationship between people and rodents. Damage done, but so cute.

So, if the sassafras also defends against being eaten, by becoming "more bad" for the animal that eats it, wouldn't that also be true in the lab.

Has anyone looked into that?  Deer like the end shoots, but the more they browse on them, and the plant gets threatened with death by ingestion, the more toxic and indigestible become the shoots. So the deer back off, and the plant can continue up, until it is taller than the browse line. Plant saved.

If plants respond to being nipped back time and again by becoming more toxic, does that happen in the lab where gnome technicians somewhere use the same sassafras plants over and over to get at the safrole oil from which they then overdose the rats? Do they do that? Go back to the same plants? If so, please check the toxicity of the oil. Does it get worse. If so, that would affect lab results. Their safrole is worse than the field safrole. Is that so? Perhaps. Nice theory.

Interesting. I recall some article about attaching electrodes to philodendron, measuring the mellow happy plant leaves, then loudly approaching with shears, clack clack and snip whack! The plant waves went nuts. Philodendron reacts to threat with fear. Is that so?

Would that plant under siege time and again react as did the evergreen - put up an additional defense to being eaten by becoming more toxic than ordinary nature. And wouldn't that skew the test results.  The animals were being given a far stronger dose than even a natural strong dose.

If so, that is another reason to toss the testing.

So, of course, noone will look into it.  Finding that the plant has outsmarted the FDA may cast doubt on the FDA.  It may help establish that we not only give substances that are not in the lab animal's diet, making it sick just because of that:  particularly rodents who need to keep gnawing and whose digestion surely reflects its need to gnaw and the juices thereof.  We also use plants that defend up.

And our stomachs may not rebel at all.  Someone needs to test whether sassafras in the field is the same degree of safrole strength as sassafras in the lab yard.  Shouldn't be hard.

Shall we use other than rats? 

Shall we test other animals for safrole?  That is also silly. No animal eats all of the sassafras. The species we looked up are selective. Even other rodents eat some parts of it, and know better than to eat what doesn't suit it.  No animal we find aims for the safrole and eats only that.

Try deer.  Deer eat parts of sassafras, some more, some less, but they also have compound stomachs for processing the woodsy things, the forage and the graze.  Wide variety.  Keep the variety, and the deer is healthy.  Overdose on something, provide too much with too little else, and it gets sick and even dies.  Surprise.  Same as the mice, same as us.

The main event is whether the sassafras itself, in addition to being allelopathic and discouraging other plants from growing around it, is also defensive in getting more toxic the more it is nibbled, or browsed.  That is the reaction of some evergreen species - the shoots and needles may well become more toxic the more the plant is under attack.  See below.  So, the plant defends itself against being eaten to death by becoming more bad for the animal.  Have some madeira, m'dear?

So:  what follows is the detail from looking this up.  Interesting to us, but the point is that we need to test the plants own capabilities and qualities and its own defenses; before we just feed stuff to animals willy nilly.
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Stress and other living things.

If plants like evergreen varieties and deciduous react to stressors in measurable ways, by becoming more toxic in the case of the shoots being eaten; or the waves from the philodendron under attack; why do we test animals in the worst stress conditions known to man - torture, overcrowding, solitary confinement, rotten diet, and then act surprised when we concoct illness and pathology. We know anxiety and fear bring on illness in us as well as stressed out, tortured lab animals - so does that environment also skew the results.

DETAILS:

1.  Natural diets.  Pay attention. A natural diet produces a healthy animal. Animals get sick on bad diets, like we do.  So should we be surprised when test animals get sick.  

2. Defenses, so the animal keeps its diet in balance.  Other plants have been found to increase in toxicity under siege, when being nibbled frequently:  Does it create in itself more toxicity, than there was before all the nibbling, as a kind of defense to being eaten to death. If so, and if the labs use the same sassafras all the time to snip snip and grind up and inject the oil, are the labs themselves creating more toxicity than out in the field over there.

3.  Is there a people connection necessarily.  Or is animal testing just another industry perpetuating itself regardless. We questioned whether that means the same bad stuff will result in people, who have different variety needs, digestive systems (that is, one stomach) and teeth (that is, do not keep growing so you don't have to gnaw all the time).

4.  We have no idea.  The FDA ban on safrole was based on its animal studies on the rats, and supposedly buttressed by human case "reports" - see ://www.answers.com/topic/sassafras/ -  in the culinary section there. Read "reports" as just that - Somebody said so.  He said that she said that he had halitosis. Gossip, that is; anecdotes, claims from Aunt Hessie who got it from Luke, or from Addie down the lane who never told what was so anyway.

5.  Stomachy ruminators. That brought us to how deer, white-tail and mule; and moose; use sassafras.  All of these have compound stomachs to break down and ferment forage and grazing products. The stomachs in multiple make it possible to ultimately digest the woodsy things, as well as eat graze, and stay healthy as long as the diet is varied, and not too much of one thing. See details about the deer, their multiple stomachs, which of them prefer sassafras shoots, which will just eat them if they are around, and more that do not seem to eat it at all.  FN 1

7.  Chewy rodents. And from there we went back to other types of rodents, and all seem to have have simple stomachs. But the rodent digestive makeup includes processing a diet consistent with gnawing - if they don't gnaw, some of their front teeth just keep growing down or down and around. Not pretty.  So their stomachs have to tolerate whatever gets in there from the gnawing process.   See details about them, this time including rabbits, groundhogs, beavers, squirrels, chipmunks etc. at FN 2.  Some eat leaves of sassafras, some cut the branches (beavers, for dams), some eat the fruit, but nobody aims directly for the safrole, apparently.
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 8.  Either type - the stomachy ruminators; or the chewy rodents; have serious differences from human makeup, and what diets are good for them.  Why should testing on them, when they need to process weird enzymes  (is there a Bambi lab?); or saw down their incisors as they eat, be valid as to illness in us, when we don't eat the same things for the same reasons. This makes no sense.  The only thing that makes sense is that no wonder we cure so little, and only suppress symptoms.

OTHER ANIMALS, AND SASSAFRAS

Do deer eat more sassafras than rats because the rats, gnawing all the time, would be more of a threat to sassafras survival?  Rats would get at the littlest shoots, and nip them right off. That could be. See ://www.sfrc.ufl.edu/4h/Sassafras/sassafra.htm/.

Groundhogs: These eat sassafras, but  not the whole plant. See ://www.answers.com/topic/sassafras/ Add to our list of sassafras eaters these new ones: black bear, and marsh rabbits. There seems to be no toxicity, aversion.

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The groundhogs and marsh rabbits also have some teeth that keep on growing, see them at ://www.hoghaven.com/study.html/, but maybe the soft sassafras is not enough to keep the teeth in check, so they do not bother. Click on the topics there.

Groundhogs do not have compound stomachs, as do deer; so they are more made for the tender parts than the woodies.  But they hibernate, which makes their systems different from mice, we understand.  But they are diffecan but they hibernate. We don't. Rabbits in winter eat the bark, however, and beavers cut the stems.

Do these differences increase or decrease the likelihood that overdosing them reflects something about us.

 Is there any animal enough like us to warrant our using their lives for ourselves? Listen to one react to that at ://www.hoghaven.com/sounds/ghs1c.wav/ Shall we test on black bears?

Generalize. Skip what you see before your eyes.

Rats and beavers and rodents, oh, my.

Beavers, chipmunks, squirrels, gophers, porcupines, gerbils, jerboas, and, Alice's favorites, rabbits and dormice. See ://animaldiversity.ummz.umich.edu/site/accounts/information/Rodentia.html/  We know that sassafras developed a defense against rodents - is that because the rodents have to gnaw, so the rodents really endanger the plant year-round? Is that so? These are indeed more like us in that they have single stomachs. But they are hugely different in that they have to keep gnawing not just for food, but to wear their teeth down so the teeth don't keep going.

Which of these mammals is most like us so that animal testing on that animal is relevant? We are neither gnawers nor browsers except on Doritos. So, pick: The compound stomach type, or the dentition going on forever type? Is our testing purely convenience of the tester and the rapid reproduction capability in tiny cages? What if that fact of perpetual tooth growth makes a difference in the animal's reaction to substances fed it for testing.

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How to conclude reasonably, that sassafras is bad for us in usual eating or drinking doses, because it is bad for rats for whom it is toxic anyway and in huge doses; and for deer (in those places where the deer eat it as preferred or tolerated food) but who react adversely any time only one food source is provided. Their diet needs variety, light browse here and graze there. That sounds more like us than the gnawers.




SASSAFRAS: A SURVIVAL POWERHOUSE

Sassafras can tolerate a great deal of encroachment by those eating it, and grows fast. It is useful as one of the first species to show up in abandoned fields, and refreshes depleted soil. Sassafras enriches it right up with its underground runners, lots of branching bushes in the understory, and big leaves.

Friday, July 17, 2009

Choctaw Indian Legend, Sassafras and the Flood. Lifesaver Raft.

The Flood: Choctaw Legend

How does sassafras attach to Native American creation legends? The picture here is not Mississippi, Choctaw country, but it sets an overall mood.

We know that sassafras was banned after inadequate testing and after thousands of years of use and reference in cultural lore in the Americas, including in religious legend.

Should we not take a second look at the discard pile.

Do go to www://choctawindian.com/, and read the tale aloud to yourself. It is sassafras that saves the life of the last human before the Flood. This is not the creation myth I was looking for from eastern countries, but this flood story may be even better.

The Choctaws are (were?) a matriarchal society, with roots in the Mississippi-Alabama areas, and seeing nature's bounty as symbolic of a mother's love. See www"//choctawindian.com/.

They lost out when the European Patriarchal and conquering cultures arrived.

Their Creation story is at that site. I found elsewhere their Great Flood story, with parallels to our Noah. The flood looks like a tsunami, rather than after a long rain. Read the www.tc.umn.edu/%7Emboucher/mikebouchweb/choctaw/flood1 for Ancient Choctaw Legend.

Tuesday, July 14, 2009

Sassafras - Seven Bedbugs In One Blow

Sassafras as Insect Repellent
Uses of Plants: A Matter of Dosage, Extraction, Information 
Give a bug enough aspirin and it, too, will expire.

Economic opportunity. Bedbug resurgencies are in the news.  See Just Try To Sleep Tight. The Bedbugs are Back at ://www.nytimes.com/2005/11/27/nyregion/27bugs.html?_r=1/  Our solution is at hand.  Put people back to work. Use sassafras wood to make your bed frame.  See ://www.woodmagazine.com/materials-guide/lumber/wood-species-3/sassafras/.  Here's more:  see://www.crabapplehillsfarm.com/chf2001/showrooms/ArkansasSassafras/ArkansasSassafras.shtml/




Use it in the kitchen, for cupboards.  Insecticides have used sassafras oil for years, from early explorer and colonial times, see current use at ://www.diatect.com/kill-bed-bug-ppc.php/. Grow your own.  See ://www.kerrysgarden.us/2006/03/01/digging-sassafras-trees/

We already know it repels rodents. Use it for children's cribs.

A multi-purpose plant. How it is used, with what dosage, with what preparation, makes the difference between a good use and a malignant one.  Just as with aspirin.

Sassafras and Cholesterol Control? Liver Detox?

Sassafras and Cholesterol Control?
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Sassafras, as a tea, made from de-barked, and minced-pounded, tender roots from the understory level,  has long been ingested as a "blood purifier."  See ://www.florahealth.com/flora/home/International/HealthInformation/Encyclopedias/Sassafras.htm/ 
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Even that mainstream site is skeptical of the ban on sassafras/safrole (issues of preparation and dosage really) but it gives a sensible overview of the status today of use of sassafras; and how a plant that used to be useful we now handily discard.  The site also gives the recipe for making tea, with the sensible precaution to use it only for 4-6 weeks over the course of a year. We can live with that. Now, to get the roots and try it. The site also offers a bibliography. See also ://www.foundationsofherbalism.com/pdf/11.pdf/.
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Issue:   High bad cholesterol; toxins building up in the liver. Some 17,000 people are waiting for liver transplants, do a search for liver transplants and get that and other stats.
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Start with the premise that centuries of use of sassafras as a "blood purifyer" produced enough good results for the practice to become widespread.  Then, logic would have it that "purifying blood" - whatever that is, but the term recurs so often in folk remedies and cultures - would be beneficial in purifying blood of its nastier cholesterol elements, and help the liver in that and other filtering actions. 
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Research in the public interest. 
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Not to criticize our national Pharma Preservation of Profits cult, but is there not a public interest component in exploring and testing folk remedies to see how and if they work, even though the ingredient cannot be patented.  Or do we only test the moneymakers?  Wrong question.
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Look up, do a search for words like blood purifier sassafras cholesterol.  Sassafras is known as a good liver detoxer and general stimulant.  See ://www.steaptv.com/2008/05/06/how-to-dandelion-tea-sassafras-tea/.  
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Liver detox.
Liver detox? What is that?  See ://www.liverdoctor.com/index.php?page=liver-detoxification/. 
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Livers go amok trying to filter out all the bad stuff we eat, drink, are exposed to environmentally that gets inside. Think great big gobs of greasy grimy fatty stuff, greasy grimy fatty stuff, greasy grimy fatty stuff, great big gobs of greasy grimy fatty stuff and me without my spoon. See, if you must, ://www.youtube.com/watch?v=EBK1RBj1sKo/ and ://www.youtube.com/watch?v=BaX95ImQcqc&NR=1/  
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Sassafras, understory close-upThe point is, if we can do little backyard remedies as in the old days, take your tonic in the spring when the little roots are nice, pare them and mash them up, the little things, and add your hot water, and go rock on the porch to health, why not. 
It often looks like surrounding vegetation.  Takes some looking when it is just taking hold in a woods of other woods.  
Beats ICU. Make some bread of it even - see ://www.ingestandimbibe.com/Articles_p/rootbeer_p.html/  And if the testing ever shows toxicity to humans in the doses we use, that, of course, is different.
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FDA,  you are interested in the proper functioning of all the Cholesterols, Healthy Livers. 
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Here is your mission, should you choose to accept it.  
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Unhinge from Pharma and profits.  Unembed yourself.  And sponsor government or other altruistic and well-funded group testing of the ordinary remedies in our back yards.  
Offer sensible dosing and preparation information, while continuing to foster regular medical checkups. Sassafras:  less toxins than in a beer beer.

Thursday, May 14, 2009

Sassafras oil. MDMA, Safrole, As Nature's "Truth Serum"

Sassafras Oil:
Use as "Truth Serum"


Ecstasy ingredient. MDMA. From safrole.

The Army considered it a possible truth serum,
tested effects on animals, lethal doses, in the 1950's;
then results of all test activity were classified until 1969, released as to effects in 1973

At issue: As a truth serum substance,
what did the Army find as to reliability,
what was it doing with it from the 1950's to 1969,
and why not use it instead of torture.

Use torture when you do not want truth, perhaps.
Use it when you want the answer you want, nothing less.
Like the Inquisition. Or fabricating other "connections" needed for political reasons.

And you will get it, often. Even if false.

For truth, why MDMA? It is the ultimate party, relax and share drug. A natural for disclosure.

Then there was FDA's sudden ban, in the 1960's,
based on anecdotal information, not reasonable testing.

All research had to stop on the "outside".

Was that for political and not scientific reasons?

Fast forward: Did Cheney and the other torture afficinados know of other,
more reliable ways of getting information than torture.
What was the decision-making process to choose.

Did they want "truth" or a "confession" to something untrue.

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Is this MDMA technique what President Obama referred to when he said that we have other ways of getting at what people know, and we do not need torture. See something like it 4/29/09 at ://www.click2houston.com/politics/19319397/detail.html.

True if you seek truth. False if you are really setting up a story line and need the person to say what you want. Like witch hunts. The Malleus Maleficarum lives. See ://www.malleusmaleficarum.org/; ://www.sacred-texts.com/pag/mm/. Yes, I am a witch. Stop. Stop! Like setting up case for war, see ://edition.cnn.com/2009/POLITICS/05/14/iraq.torture/

Whichever way that political issue goes, meanwhile, here we look at ways to get true information: sassafras derivative, benign; or torture, malignant. What are the factors.

Here is something the Army has known about for decades: MDMA. And we ask what did it do with it? Or the CIA. Which had what is unclear. Did they share? Explore further? Why not?

Interesting to us: there is a long-known capability of the ecstasy drug ingredient, MDMA. This is extracted from safrole or sassafras oil, and it lowers people's defenses, produces euphoria, a state of mind where the person just wants to share. Ecstasy. Would you believe? A way to force disclosures?

Use as a truth serum mechanism. There have been other forays into truth serums (sera? que sera?) see Center for Cognitive Liberty and Ethics at ://www.cognitiveliberty.org/8jcl/8JCL77.html/. But could the use of truth serums be in itself a kind of torture. See ://www.cbsnews.com/stories/2003/04/07/60II/main548221.shtml/ No easy answers. But the kind of drug used, and in what dose and with what effects, could make the difference.

Still, we have the current need of our military/ intelligence community to get reliable disclosures of information from captives. This assumes their instructions are to get truth, and not just words to fill in what is needed to make a story line, forced but false confessions to close the case. For truth, does the Army indeed use, or could they; and can they not substitute, sassafras/ecstasy as a productive alternative to torture. Torture is illegal, immoral and ineffective even in a time-bomb scenario (who has time to waterboard over a hundred times; and still the person may lie). Anything to stop the pain.
    • Yet is this use of ecstasy really off limits because it was banned by the FDA in the 1960's or so? Or was the ban helpful to the Army/ CIA in keeping its information to itself for decades. A ban for political and not scientific health reasons. Top Secret. If so, it failed. People know and knew what ecstasy produced. If the Army had it, why did they not use it - why go to torture instead? Just because torture is more satisfying to the Cheney-type mesomorphs in charge, preferring muscle? See Fear of Fog, Ectomorphs, Mesomorphs. Whose interest is served by the ban. Intelligence at work? Or lack of. All depends on the purpose for the torture: Truth, bad choice. Get what you want, good choice.
    • For instant overview, and the politics involved in the handling of MDMA and its speed-of-light ban, 3,4-methylenedioxmethamphetamine, see Substance Abuse, A Comprehensive Textbook, by Charles S. Grob and Russell L. Polond, at http://www.drugtext.org/library/research/mdma/archive/15/default.htm/ at 24 MDMA. FN 2
    Sections here:
    I. The bad effects of MDMA, at high doses (Army used lethal), problems of adulteration, misuse

    II. Potential of MDMA as a "truth serum", everybody relax and togetherness abounds

    III. What We Know About Testing So Far: Still learning.
    .
    a) MDMA as Army Experimental Agent 1475, or EA-1475, or ea1475
    b) Testing and Consent Issues: Who was used, if anybody. Human testing? In the gap 20 years?

    IV. Good Uses for MDMA - Therapies, No Need for Torture; Other.

    V. Was the FDA ban for political, economic even military reasons, but not scientific as to the public's access with reasonable information, dosing

    Footnotes. Substantive here. Read especially FN 2, the Grob and Polond text summary.

    ................................................................................
    .
    I. Bad health effects of using MDMA

    The bad news comes before the good, so you can compare these kinds of effects of a drug to the bad effects of torture on someone.

    MDMA was tested by the US Army in the 1950's, but only on animals, and the results were released in the 1970's (why the delay?) as to those high doses in animals. Declassification only in 1969, says this site, MDMA Drug Information, at Medic8 Drug Information, at ://www.medic8.com/medicines/MDMA.html/ These were "lethal dose" studies, see the Drug Information site. MDMA is also known as Mud, Molly or Madman. Good summary at that long site. Similar topics to our FN 2, the Golb and Polond text. A/k/a Adam for MDMA.

    Adverse reactions: See also FN 2, Golb and Polond; and Medic8.

    Here is a list from a Philip Wolfson, Journal of Psychoactive Drugs Vol.18/4 1986, his book Meeting at the Edge with Adam: A Man For All Seasons, (Adam is another name for MDMA). He is/was a psychotherapist who believed that using MDMA may open new possibilities for psychotherapy treatment, when used in conjunction with it.

    See the quotation and discussion at E for Ecstasy by a Nicholas Saunders, appendices to 1993 book, at ://paranoia.lycaeum.org/mdma/e.for.ecstasy.append/ There, Wolfson is attributed with this list. How much of this is high-dose related?

    "(1) Severe and potentially fatal reactions can occur unpredictably on occasions.
    (2) Seizures are said to have occurred.
    (3) MDMA may reduce resistance to infection.
    (4) MDMA causes increase in blood pressure.
    (5) A variety of short-term reactions may occur, sometimes persisting or recurring for several months, including anxiety and insomnia. A client's judgment can be interfered with by their heightened sense of excitement under MDMA.
    (6) MDMA has no established safety record - the necessary experiments have not been made." (emphasis added)
    The government does not list any of those reactions, however - and only shows official concern that there can be adulterants in the mix that can be harmful - otherwise, little reason to ban it except that people like it and "abuse it" - see that at US Dept of Justice, DEA, Drug Information, at //www.usdoj.gov/dea/concern/mdma.html/

    II. Potential of MDMA as a "Truth Serum" Type Technique

    More from Wolfson at the Saunders book site at ://paranoia.lycaeum.org/mdma/e.for.ecstasy.append (yes, this is totem pole hearsay, but you are alerted so you yourself can go vet)
    .

    "He (Wolfson) says that MDMA is unique because:

    "1. It offers a rapid and significant break with people's defence structures.
    2. It can facilitate a shift from a state of self-hatred to one of love of self and others.
    3. It encourages people to shift from isolation to contact and intimacy and from withholding
    to giving.
    4. When MDMA has given them a more positive attitude, people find it easier to make decisions."

    III. What Have Know About the Testing-Non-Testing So Far

    A. Ask the Army. They know.

    What we know is from the Saunders site, Grob and Polond at FN 2, the Medic8 site, and others as shown here.

    First, the Saunders site. Again we are using wonderful totem-pole hearsay. Do a "find" for that at ://caselaw.lp.findlaw.com/scripts/getcase.pl?court=ma&vol=appslip/17416&invol=1/. In short, totem pole hearsay is like the old Listerine commercial - he says that she says that he has halitosis.

    The report is from a Rick Doblin, president, Multi-Disciplinary Association for Psychedelic Studies, in the US (the Saunders site is British). Doblin presented this as part of his dissertation at Harvard's Kennedy School of Government, see ://www.maps.org/staff.html/.

    "1. Report of US Army tests on MDMA, from Rick Doblin president of the Multi-disciplinary Association for Psychedelic Studies in the U.S.

    "In the 1950's, MDMA was one of the analogs of MDA that were given to animals by the U.S. army at the Edgwood Arsenal, which was then investigating drugs for use in chemical warfare. There is no evidence in the public domain to indicate that MDMA, which was code named EA-1475 (Experimental Agent 1475), was ever given to humans or was tried as a truth serum." (emphasis supplied)
      Discussion:

      Well, why not give it to humans or try it as a truth serum? It looks like the Army did. This was before the ban. Are you kidding us? That's what the Army does - force information from people. Why don't we believe that the Army just left it alone.

      Here is Point A. There is Point B. Connect the dots.

      If MDMA was not followed up, perhaps it was just too soft to satisfy military people. Use a nice gurney and a quiet room to get reliable information? No, we are the Army. We like blood. Screams. Punish, and personally, even if it is against self-interest. And takes 138 times to get something. Or more, or less.

      Tentative conclusion:

      Apparently we still have a tool available in MDMA, from sassafras; that remains largely untested, because either the Army will not do it out of honor; or they have done it and have found it extremely effective, so it must be kept Top Secret.

      Yet, here it is on the internet. We see as ordinary people following dots that safrole/MDMA appears to have great potential in fostering reliable disclosures because that is what the substance does - from the old hospitality drink of Native Americans, see Sassafras and History, International and Historical Uses, to today - MDMA fosters trust, openness, togetherness, fuzzy feelings. It has been considered as a "truth serum" before. See ://www.psychonaut.com/index.php?option=com_jd-wiki&Itemid=&id=mdma/
      • That Psychonaut site notes that the Army in the 1950's MDMA was found "unsuitable" for the purpose, a truth serum. And never (they say) tested people. Just overdosed animals.
      And the Army never released its results on the animals until 1973 - twenty years later. See the Medic8 site.

      Declassification until 1969, and still not released for a further 4 years? Does this raise any questions, class? The sites at Psychonaut and Medic8 note the effect of the drug, to promote, in sum, "togetherness." Are we to believe that the Army only looked for lethal side effects possibly, and so they released those results only and very late in 1973? That they never tested out its truth-forcing? When that is their job?

      B. Testing worries.

      Who were the test subjects? If there were any during the 20 years between the "study" and the release of results, heh heh. Did the people know they were being tested. Was consent freely given, and in writing as required by the Geneva Convention, see ://academic.udayton.edu/health/05bioethics/01taylors.htm. What happened to them, the people tested, if any were. Military testing: see ://www.humanrights-geneva.info/US-A-long-and-disturbing-history,2972/
      .
      And are the side and after affects really more benign than in torture. If not, say so. Look at FN 2 and Medic8 for more on side effects. At this point, however, it looks like with proper dosing, bad side effects could well be avoided. We know what dosing gets used in these kinds of tests, we think. Geared to produce the worst.
      • What do various sites say, and, yes, they do speak: See the effects the drug produces, and the responses - horrors - it works, or just might.
      MDMA.net:
      "The heightened emotional responsiveness, lowering of defensive barriers, openness and sense of closeness to others induced by MDMA can promote an honesty of self-disclosure that might be manipulated for malign ends. Fortunately, this hasn't yet happened on an organised scale." ://www.mdma.net/
      This quotation is from a site exploring the history and uses of MDMA. Note the boy scout reluctance to use it because it could be used "for malignant ends." Effectiveness as a truth serum: This is still open.

      Army testing. Back to that. What is wrong here. See again the brief overview of the experiments at MDMA at ://www.mdma.net/. Short, but detailed: A helpful place for summary as well.

      Everybody knows that the Army looked at it as a truth serum, but nobody knows what they saw. Just that suddenly, after the Army testing in the fifties, the bans came in the sixties and seventies. Look at FN 2 for the pressures on the scientists.
      .
      Meanwhile, shall we spike the UN punch? For a little togetherness?
      .
      IV. Why Has MDMA Been Ignored.
      It seems to do what it says - people just love to open up with it

      Maddow, Olbermann, all the talkies who do more than just churn opinions, you have high priced explorers on the roster. I am a little old lady in sneakers and putting stuff together that looks interesting. Join in.
      .
      So far, we are told that truth serums are not foolproof, and someone still can mislead a questioner when in the twilight, see Sassafras Tree, Natural Pragmatism, Truth Serum Idea. No more reliable than torture, say. And we know you may have to do that 138 times to get what you want, if you ever do, and by then the ticking bomb is boom. Was MDMA included in those overviews of drugs?

      Back of old medicine cabinet. What is inside? Dare we look?

      Have we really looked in the cupboard, to see what there is other than torture? Turn it around!

      No. Nobody has tested MDMA for its use as a truth serum, on the public record that we see so far. Is the lack of research because the FDA has banned it? Then lift the ban, or narrow it. We can't touch that. Do we believe that would stop the Army.

      All the ban does is stop research, and regular people from checking the scientific bases for the bans, and whether less restrictive alternatives are scientifically supported here. FN 1.

      V. Good uses for MDMA, possibly.

      Treatments. Benign recreation.
      A matter of dose, like alcohol

      And, of course, avoid Torture.
      • MDMA widely spread among psychotherapists in the 50's-60's ff. As ecstasy, it became known as a psychedelic hug drug - "Adam" for a shortcut name. FN 1. That was an era of using drugs in therapies, and much of that may well have been a fad and later debunked; but a spin-off for disclosure purposes surely can be explored.
      See this google book (copy and paste the address, long as it is) Speed, Ecstasy, Ritalin, The Science of Amphetamines, 2006, by Prof. Leslie Iversen, Ph.D., Dept. of Pharmacology, Oxford Univ., at Section 8.1, page 149-150 ff, Chemistry and history.

      The site is a long URL - copy and paste at ://books.google.com/books?id=CkAaAZRLfOcC&pg=PA150&lpg=PA150&dq=sassafras+tree+truth+serum&source=bl&ots=U1tVm1MsFj&sig=eRioOVlwhjv2tTs2rHSIAkmmvy4&hl=en&ei=xeMLSqaFLOKntgfw1OH0Bw&sa=X&oi=book_result&ct=result&resnum=5#PPA149,M1/.

      That book is reviewed in 2006 at ://www.newscientist.com/article/mg19125622.200/

      If so, it is all the more damning that we did not choose to use it over torture.

      Discussion:

      As a culture, is this true: That we prefer research into, the process of, and application of torture, that is, punishment; to using something that might be pleasurable to get the job done, and done more reliably: MDMA. Is all that is pleasure, sinful? Are we still stuck in that?
      .

      V. Ban for Cultural and Political Reasons, not Scientific

      That is what it looks like, after all this time looking at the angles. MDMA is a safrole, or sassafras oil, extract long used and long-banned as a psychedelic, pleasurable. And look at the outcry against researching its good uses, and promoting torture instead by opposing investigating, challenging the use of torture. See FN 1 for the non-merits of the ban on safrole; and FN 2 for assessments of the grounding of the ban. Note that no rat, even though allergic in the sense of being in an allelopathic relationship with sassafras, got tumors when doses were used like those humans would, proportional. Don't let that idea out.

      So, we don't and won't use this potential resource if we need to get information from people, as apparently we do need, if research were allowed to continue on it. The reason sassafras is not researched is 1) the ban, cultural rather than scientific, see FN 1; and 2) value judgments, that if it works, it might be used for malign ends.

      If we aren't already malign in using torture, who is?

      ................................................................................


      FN 1 History. Ecstasy spread to yuppies in the '80's. Intense rapturous delight! More! The DEA banned it, even from medical use, over objections of those who sought a less restrictive control, see the Iversen book at 151. But addiction and finding brain damage - how was that done. Again, it was in those rats who are allergic anyway - yet, it was enough to ban it all as to humans.

      And that was so even though there were no tumors even in the rats at dosage levels like humans would use, proportional. Nonetheless, look what happened.
      • A judge ordered it to be available by prescription and for research, not banned; but the DEA put it on the full ban list anyway. Iversen at page 152. Where is the science, and where is the culture. Guess.

        The ban, however, just curtailed the research - attitudes of the recreationally minded did not change. The controversy over the ban was free advertising.

        Idea - The government will not foster unfixed testing (they use huge doses on rats already allergic to it, so no wonder the rats get tumored)
      • because sassafras grows in our back yards, and
      • we might make what we want ourselves, and then
      • what profit would the Manufacturers and the lobbyists and Pharma make.
      Today, that argument gets bigger: This is a recession, so we can't have people doing for themselves and putting other people out of work. They need to buy. And the ultimate argument: ban it because sassafras is an ingredient in ecstasy, and we can't have that, either. A cultural reason.

      Guard your pies, pickles, children's stories and vanilla, mmmmmm. And lawns.

      The safrole extract needed for ecstasy is also in "nutmeg... dill, parsley seed, crocus (such a pretty yard. You say you are having a lawn party?), saffron, vanilla bean, and calamus." Also the above-ground woody part of another tree, the Ocotea pretiosa. See the Speed, Ecstasy, Ritalin book above.
      .
      For Ocotea pretiosa, see ://www.spiritgarden.co.uk/cart/index.pl/catid_5/proid_108/_/_/BrazilianSassafras/OcoteaPretiosa

      Brer Rabbit?

      He loves calamus. Calamus is in The List there, of substances with safrole. It was/is a common digestive with nice side effects. See it at mealtime at Uncle Remus Tales, Translations: Uncle Remus Initiates the Little Boy; and, same site, Calamus Root Side Note.

      .......................................................................
      FN 2. Grob and Polond textbook section on MDMA, looks like chapter 24 there.

      Topics on MDMA include:

      History,
      Epidemiology,
      Potential Treatment Applications, but before beneficial-purpose testing could be done, it was banned - on the most restrictive Schedule 1. Even smoking and drinking decreased while subjects in earlier studies were using ecstasy in controlled settings.

      On to Adverse Clinical Effects, not seen in healthy, occasional, moderate users; but in excess - as with liguor, we suppose. Also there are issues of amateur "manufacture" and purity and quality of what is marketed. Like the stills of white lightning? Also issues of pre-exisiting medical vulnerabilities. Long section on the bad effects and on whom and when and why.

      Then on to Neurotoxicity. No link necessarily. Lab animals show effects of serotonin change, but not lasting. Extending animal results to human has been inconclusive. Go read the whole thing. Too detailed for here.

      Then the zinger in the field - political and economic agendas invading the scientific arena. There are pressures on the scientists to ally their findings with conventional "expectations."

      Science vs. politics. When will science prevail. Obama? Your turn.

      Saturday, March 28, 2009

      Sassafras Elixir Recipes. Tea - from history. Indian, Colonial, European, Virginia.

       First Aid, Cures and Enjoyment
      .
      Sassafras Recipes for One and All
      From History
      .
      As we find them. Posts to continue.
      .
      I.  Recipes from the old days

      Note that if you would like a little sweetener with your sassafras, or to help the medicine go down, avoid high fructose corn syrup. It is marketed freely, despite enough findings of likely mercury to ban it, if the FDA were consistent.  See ://www.celsias.com/article/hfcs/; see also ://www.highfructosecornsyrup.org/2009/02/sweetness-and-blight-why-is-fda.html/. Apparently it meets some standard of  "natural" - see ://www.columbiatribune.com/news/2009/feb/04/is-mercury-lurking-in-high-fructose-corn-syrup/ - whereas safrole does not?  But the FDA refuses to define "natural" - leading to the inconsistency. See ://www.foodnavigator-usa.com/Financial-Industry/Natural-will-remain-undefined-says-FDA

      .
      Sassafras tea.*
      ...............................................................................................
      * A layman's disclaimer  Arguments against: see http://www.bccancer.bc.ca/PPI/UnconventionalTherapies/SassafrasTea.htm/ All hinges on whether that 1960's testing on rats (leading to the 1975 ban) who are themselves averse to sassafras and would never eat it, is valid as an indicator of cancer in people.  Debaters, start your root beer.  And note other sources that say the amount of carcinogen in sassafras is 1/14 of that in beer. See://www.florahealth.com/flora/home/Canada/HealthInformation/Encyclopedias/Sassafras.htm/ Why doesn't the FDA ban beer? Let's test the rats for beer the same way that sassafras was tested, except that is cruel. Idea is, see why we need testing to be consistent and reasonable?  FN 1
      .............................................................................................

       Modern recipes:  see ://answers.yahoo.com/question/index?qid=20080608171520AAKjFKG/ = scroll down past the usual overview to someone's comment that describes uses in Virginia. 
      • Use the root, not the leaves. The root has an outer bark on it, and you take that off and wash the root well. Get 3-4 roots that are 4-6 inches long. Chop in small pieces . Boil a gallon of water and drop in the pieces. Boil 15-20 minutes, or longer for stronger. Good also with honey.
      • For using the leaves:  Boil water and pour over leaves and let steep for 20 minutes. Use 1 tsp dried leaves to 1 cup water.  Strain out the leaves before drinking. 
      • Here is somebody's video - for watching. Note everybody smelling the root every chance they get. Visit ://www.youtube.com/watch?v=wxp0Nm-1qOc
      Sassafras country. Around the reservoir.Note that in the video (no sound available) the people use a simple potato peeler to peel off the dark outside of the root, and use roots about a middle finger in diameter.

      Not as big as a thumb.  They cut that into fingerlengths or less, and then pound them a bit with a meat tenderizer pounder until they are flatter and somewhat pulpy. Then they add the boiling water to make the tea.  That makes sense.  Speeds up the infusion if the root bits are softened down first. And they do keep smelling it all the time. Have to get some.
      • This sassafras tea recipe uses a grater as well as a vegetable peeler, and explains about layers of the bark on the roots. Use spring roots, scrub and peel the outside darkest part, and use the under color.  Leaves are best picked in August, it says, and the file loses flavor over time, so keep going back to grind new ones for your gumbo. When  does fostering hospitality become a party. A natural party. Also an issue for alcohol. All in the dose, like anything else. See ://www.practicallyedible.com/edible.nsf/pages/sassafrass
      Sassafras has been used for healing many diseases. Here, Spanish soldiers had become sick, and a French survivor of a Spanish attack on French Huguenots told of this Indian cure:
      • Dig up sassafras root. Cut it in small pieces. Put as much as needed into water. Leave the root in the water until it takes on a good color. The patient then drinks it at breakfast and supper, without regard to quantity.  
      This, from the Indians, noted in "A Role for Sassafras in the Search for the Lost Colony," by Philip F. McMullan, Jr.at ://www.lost-colony.com/Philpaper.pdf/  Lost Colony at 21. The Lost Colony treatise refers to another treatis, from 1574, by a Spanish Doctor Nicolas Monardes, on the uses of sassafras   "Joyfull newes out of the new founde worlde."  The Joyfull Newes was published in London in 1596. We are trying to find it. We are looking for the translation by John Frampton, who was an English merchant who spent much time in Spain. This Monardes information is at page 31 of Lost Colony.

      II.  A Look to the Past

      Get the flavor of the early uses in these fair use quotes, from Voyages of the English nation to America, Richard Hakluyt (very early, but what year? see://www.archive.org/stream/cu31924024759395/cu31924024759395_djvu.txt
      moreouer, they told vs, 
      
      that the vertue of that tree was, to heale any other disease : the 
      
      tree is in their language called Ameda or Hanneda, this is 
      
      thought to be the Sassafras tree. Our Captaine presently caused 
      
      some of that drink to be made for his men to drink of it, but 
      
      there was none durst tast of it, except one or two, who 
      
      ventured the drinking of it, only to tast and proue it : the other 
      
      seeing that did the like, and presently recouered their health 
      
      and were deliuered of that sickenes, and what other disease 
      
      soeuer, in such sorte, that there were some had bene diseased 
      
      and troubled with the French Pockes foure or fiue 
      
      remedy yeres, and with this drinke were cleane healed. 
      
      .igainst the After this medicine was found and proued to be true 
      
      French Pocks * 
      
      We cannot find how to designate this page, so do a "find" for sassafras at that full text site, and it appears at about the first 25% spot on the sliding scroll har to the right of the text page.


      We found the full text of another treatise, Plants and Plant Science in Latin America, at http://www.archive.org/stream/plantsandplantsc033403mbp/plantsandplantsc033403mbp_djvu.txt/  Do a "fiind" for sassafras, and each instance of it will be highlighted in the text. Find distilling the essential oil,
      a Frenche man that had bene 
      in those partes shewed me a pece of yt, and tolde me marvells 
      of the vertues thereof, and howe many and variable diseases 
      were healed with the water which was made of it, and I judged 
      that, which nowe I doe finde to be true and have seene by 
      experience. He tolde me that the Frenchemen which had bene 
      in the Florida, at the time when they came into those partes had 
      bene sicke the moste of them of grevous and variable diseases, 
      and that the Indians did shewe them this tree, and the manner 
      howe they shoulde vse yt, &c ; so they did, and were healed of 
      many evillsj which surely bringeth admiration that one onely 
      remedy shoulde worke so variable and marvelous effectes. The 
      name of this tree, as the Indyans terme yt, is called Pauame, 
      and the Frenchemen called it Sassafras. To be brefe, the 
      Doctor Monardus bestoweth eleven leaves in describinge the 
      sovereinties and excellent properties thereof. 
      
      That looks like the circumstance of the use of the tea, above. People also ate for days nothing but a porridge of sassafras leaves.
      much as in foure dayes wee had done against the same : 
      we lodged vpon an Hand, where wee had nothing in the world to 
      eate but pottage of Sassafras leaues, the like whereof for a meate 
      was neuer used before as I thinke 
      
      ..................................................................................

      III. Sassafras for health and well-being:  

      For us, it takes a society to give any credence to benefiting people other than through drugs manufactured and  bottled.  One with some success in this area is the Center for Mind-Body Medicine, James. S. Gordon, M.D. The Center collects, researches, gets the word out about choices, by Organizing It.  Letter to editor, NYT 5/26/2009 page D4. See ://www.cmbm.org/

      Have to see if that group has researched sassafras.

      At one time, the sassafras was considered the miracle tree. All we need is dosing and preparation information. And Stimulus Payments for a new industry backed by sound research on reasonable dosing and preparation. Does a form of simple universal health care consist in a Sassafras in Every Yard?

      Sassafras is indigenous to North America, and introduced to Europe by early explorers, in about 1584. The story of the earlly colonies and explorers, especially as they found sassafras uses of the Indians, and tried to track the fate of a lost colony in Virginia, is at the Lost Colony site, above. It describes the saga of a "lost" Virginia colony, that had disappeared - all 116 souls - by the time help returned from England. 


      Enjoy the full histories and description - especially of the fragrance of the sassafras when the Indians engaged in the annual burn-back of the lower growths in the forests. Wafted with a sweet arome even out to the ships. Sassafras, like anything else, can be abused by excessive use, see page 22.


      The explorers found them "effective and safe" when not in excess. even healing scurvy and other mariners; ailments from long shipboarding. So again we are not at a ban of sassafras, but dosing information and preparation, as with anything else.  Do you chew seventeen teabags in an hour for six hours? Probably not. If you did,  and long enough, probably you too would get a tumor somewhere.

      IV.  SLOAN-KETTERING.  Let's get it straight from the horse's mouth.


      Are you detached enough from Pharma to fund testing of sassafras without using rats? Or other allelopathic animals, if indeed you have to use animals at all.

      We ask because we think that venerable Sloan-Kettering surely would support finding out if the test animals are in an allelopathic relationship to the substance being tested, before drawing conclusions of those poor critters get tumors.  See ://www.mskcc.org/mskcc/html/11790.cfm?Disclaimer_Redirect=%2Fmskcc%2Fhtml%2F69363.cfm/

      We find nothing on questioning which animals are used for what substances. Surely there is someone out there who delved into why we use rodents for plant and drug testing without first finding out for sure if that substance is part of their normal diet. The idea of extrapolating as we do makes anybody sick.
      And while you are at it, SK, please test beer against sassafras tea.  Thanks.  Start with the good Dr. Duke at ://www.florahealth.com/flora/home/Canada/HealthInformation/Encyclopedias/Sassafras.htm/
      ...............................................................................
      FN 1 Dr. Duke has ideas. Ask Sloan Kettering to check it out.

      Saturday, March 21, 2009

      Sassafras and the American Slave Tradition. Our Own History

       The Wisdom of the Folk Remedy
      Not To Be Disregarded.

      What trace elements in the natural cure or use 
      cannot be replicated in the laboratory substitute, if any



      Folk remedies. FN 1

       .
      Use and pass on the lore, because the materials are at hand, no extra cost, and there are enough experience, anecdotes, recipes, to make it reasonably safe.  There is no alternative where there is no money. Who to trust?  The healer, the old ways.

      Hear Slave Narratives at The Gutenberg Project, at ://infomotions.com/etexts/gutenberg/dirs/1/1/4/2/11422/11422.htm.  Do a "find" for sassafras, and see this: Charlie Vaden, then age 72, lived in Green Grove, Arkansas, and was interviewed as part of the project about slave and black lore. Scroll up to the beginning of the entries related to him.  Farmer.  He remembers uses for garlic as a poultice for neuralgia, and this: "Sassafras is a good tea, a good blood purifier in the spring of the year." At another entry, from A Folk History of Slavery,  after a whipping, slaves used sassafras as medicine.  See http://www.fullbooks.com/Slave-Narratives-A-Folk-History-of-Slaveryx14332.html: "We used snake root, hohound weed, life everlastin' weed, horse mint an' sassafras as medicine."

      Gumbo file and slave cooking - see Slavery in America at ://www.slaveryinamerica.org/history /hs_es_cuisine.htm/.  A stew of vegetables, crawfish, chicken, pork. "The stew is thickened with powder from sassafras leaves."  Find that section by a "find" for sassafras. The term gumbo comes from African roots, :kngombo, or ochingombo.

      During the Civil War, the blockades of the southern ports, people (not just slaves) "brewed a decoction of blackberry leaves and sassafras roots to take the place of tea." See Slavery: Islamic and Christian Perspectives, a bit of lore in an overall site looking with a new eye at our interpretations of ourselves, at ://www.al-islam.org/slavery/12.htm/

      A search for "slavery" and "sassafras" turns up uses for sassafras in dyes, and liquor.

      Then there is Daddy Jack, from the Uncle Remus tradition, there bundling sassafras roots when the little boy comes to find Uncle Remus.  See the Gutenberg Project at ://www.gutenberg.org/ebooks/26429 /  Do the "find" for sassafras to get to it.  A normal part of everyday life. Sassafras.

      Now maligned and its possibilities cut off.

      ...............................................
      FN 1  Do a search for Pharma and natural remedies and see all the sites where there is no testing result available because noone will or can pay for the testing where there is no  profit to the substance in marketing.

      Still, the history of sassafras and other herbs leads to the conclusion that keys are there. Not miracles, but perhaps keys to why they worked so long for so many.  The well-to-do may well continue with their modern pills, but also let the poor as well as others who prefer the natural to the pill, have the information needed to use those substances safely.

      Dese Doses Do Good. Dose Doses Do Bad. So, Inform About Da Dose. A family Bronx slant for Sassafras.

      Have You Ever Seen a Foodstuff
      A Foodstuff, A Foodstuff.

      Have you ever seen a foodstuff
      That couldn't make you sick.

      Take this dose and that dose,
      Take this dose and that dose.

      Have you ever seen a foodstuff
      That couldn't make you sick.



      If the topic of reviews on the initial 1970's -1970's sassafras testing on rodents is new to you, see the overview, and the results, at  ://www.planetherbs.com/theory/notes-on-herb-drug-and-herb-herb-contraindications.html/. 

      It explains why we want a recount.If safrole oil is the problem, safrole is also in mace, nutmeg, basil, black pepper, rosemary, dill, black tea, dang gui, tamarind, cinnamon, witch hazel, and Asian wild ginger, see this list at Planet Herbs. And a cup of sassafras tea is 1/14 (one-fourteenth) as carcinogenic as a cup of beer. Also Planet Herbs. Good reason to re-look.

      History tells of many uses of sassafras parts (leaf, root, bark) and in various doses and preparations. Use this part for that remedy, that part for that other one. Safrole, the oil from the bark, seems to be the main issue for claims of carcinogenic qualities, but that came from rat testing, and it appears that rats are naturally averse to safrole. Is that a reasonable test to apply to humans? FN 1

      And can the safrole issue, if there really is one, be approached with dosing information - as we do with alcohol and cigarettes. If there is that connection, and it is only claimed - nothing like the cause and effect we already have with the booze and tobacco.

      The historic uses include, as summary:
      • healing,
      • hospitality (a nice relaxer, think happy thoughts) - take too much and maybe you hallucinate, or use it toward that end with something else.
      • flavoring,
      • aromas,
      • digestion issues, flatulence
      • an emetic - take too much and you get vomiting
      • even for family planning - take too much at the wrong time, and you may not have wanted that result. An abortifacient. Or maybe you did. What did Great-Granny do? Or even Eve - she had those first two, then waited until they were grown before having her third. How did she do that? See other essential oils that are characterized as abortifacients at ://www.essentialoils.co.za/abortifacient-oils.htm/  A matter of degree, and the objective.
      No, stay away, says drugs.com. Sassafras produces vomiting, hallucinations, etc. ://www.drugs.com/npp/sassafras.html. Obviously the total ban desription at that site is false, because we use file in cooking, and file gumbo, ground sassafras, is delicious as a thickening agent. Dose control.

      Why not just inform and warn about what does is needed for what purpose. Improper dosing of anything makes you sick. Alcohol, cigarettes, sugar.

      Here is why, so far, we think
      • Sassafras grows all over. It is too accessible, too cheap, no profit to industry. So is it really industry pressure to preserve its own profits, combined with cultural issues (the family planning, the relaxer-nice thoughts part) that drive the FDA?
      • Nobody likes to admit an error. So say there is new information, and then you don't have to. Can we move beyond that and just review the testing done here, the test animals and their relationship to the substance.
      Then, if other species are used, with reasonable doses (again, anything will make anybody sick if taken in unreasonable quentities), then the issue becomes this:

      Sassafras Police - Watching Your Woods

      Does warning and information about dosing suffice. Why a total ban? Have we no heads? If quantity is a problem in case someone wants to make another substance out of it, put it behnd the counter, like Sudafed. Big deal.

      Avoid the sloppy generalizing. Separate out the uses of leaves from uses of root and bark.

      ......................................................

      FN 1. Monitor the FDA testing.

      If it is true, as other posts offered here with specific site references suggest,
      • that rodents were used in the testing; and
      • that huge and constant ingestion of the substance was forced on the rodents with the predictable result of sickness and death; and, in addition,
      • that rodents (including rats, mice, beavers) have a naturally allelopathic relationship to sassafras - the plant makes them sick as a defensive mechanism of the plant itself against being eaten, as for beaver dams, for example); and
      • that the testing method was influenced by industry who sought broader use of patentable and profitable lab substances, not the everywhere sassafras, and
      • that the FDA assumes (there is legislation creating that assumption, of sorts) that any carcinogenic property as to rodents, even in that allelopathic relationship to the plant being tested, means danger to humans; and
      • that the FDA then fully bans the substance, while permitting similarly health-endangering substances such as alcohol and cigarettes to be marketed with usual warnings as to dosage and ordinary use at table ir in bottle continuing uninterrupted; and
      • nobody tests the testing done in the first place; and
      • our root beer tastes bad; then
      On what ground is the drug industry site so positive about its statements about safrole as carcinogenic, dangerous.

      We want that recount. Maybe the FDA is right; the ill effect is repeated in test animals that are not rodents.  We prefer no animal testing, but if that is what we have, at least steer clear of the rodents with sassafras. . And maybe the safrole hype is hype.

      Friday, March 20, 2009

      Sassafras and Guantanamo; Retest Safrole and Apply, If Applicable

      Sassafras. The hospitality tea.

      The feel-good root-beer component, just from the bark of the sassafras tree, not an additive, not a "drug," part of a food. And available all over America at one time, and even now.

      Consider its ancient hospitality use: Native Americans, others, see the history of the uses of sassafras, at this site. Yet, even a site that says it explains "dangers" never finds any, all is hearsay, there has been no testing as is done when Pharma is seeking a patent (can't patent the sassafras). So what is the problem?

      You read it. The title has no bearing on the content, at Lifescript.com - ://www.lifescript.com/Health/Alternative-Therapies/Herbs/The_Dangers_Of_Sassafras.aspx?trans=1&du=1&gclid=COrd7-O0spkCFQu-GgodUz6y7w&ef_id=1350:3:c_6077ee56874670969761bdf470921909_2540435225:TIGaiEo-KR4AAB-JJuMAAAAS:20090320210705/

      .
      The site otherwise gives a good history of its traditional uses. Are these folks on Pharma's payroll?

      Cultural use: facilitation.

      Invite the stranger in your home, offer hearth and food, and the last thing you need is someone getting up in the night and beating everyone to death and making off with your possessions. The colonials - here is a brew that makes you feel good. It may not cure, but you feel better. Sassafras tea. In great demand.

      Now: We have at Guantanamo a number of people who hate us, as anyone with an ideological difference and experience of torture would.

      If safrole is not really carcinogenic to people - that is the important point.

      Sassafras Remedies - A Pharmacology List

      Step Right Up

      We do need serious testing on this plant, leaves, roots, bark, all used in different ways historically.

      Does someone know if the FDA has withdrawn its concern for safrole? Here is a site that touts its uses with no mention of anything carcinogenic - for rats or anything else - and that is a surprise.

      Visit ://dotcrawler.com/natural-herbs.html. Find uses such as for:
      • stimulant
      • diaphoretic (?)
      • alterative (?)
      • add "qualacum of sarsaparilla" and treat your rheumatism
      • distill the bark for soaps and a yellow dye (so no ingesting)
      • the young shoots are used for beer (these would be the ones that the rats are allelopathic toward, so the plant defends itself?)
      • the "pith variety" has mucilant in it and is used as an emulcent
      • catarrhal infection
      • syphilis
      • pain of periods
      • dental disinfectant
      There.

      Now: On to testosterone. Reports that the roots contain testosterone are mixed: see ://www.planbecovillage.org/native-plants.php/ Scroll down. They describe the way the plant spreads - those underground runners - as 'suckering'.

      Add uses:
      • mosquito repellent (great now that we seem to lost our bats).
      • Use the shoots to make a drink, and add yeast for carbonation - root beer (we knew that one)
      • add some sassafras to your moonshine.
      • antidiarrheal
      • measles
      • chew the roots for bad breath
      • poultice for wounds
      • eyewash for sore eyes
      Sassafras. A sight for sore eyes?

      And finally, sassafras for family planning. See ://www.drugs.com/npp/sassafras.html. Is that the real reason, a cultural one, for treating sassafras differently from other matters where we are merely warned and informed? Impatience with abortifacience? Abortifacient. Do you dare say it. Might reasonable, intelligent, moral people want information? Who decides?